We are proud to share that our team has worked on a NEW STUDY to evaluate the safety and efficacy of a formulation based on Hyaluronic Acid and Tamarind Seed Extract, for Esophageal Mucosal Protection from Acid Insult.

The mode of action of the formulation relies on natural extracts and bioadhesive compounds to create a mechanical barrier without disrupting the natural equilibrium of the esophageal epithelium.

TESTS AND ANALYSIS PERFORMED

The Safety of the Technology has been confirmed through a variety of assays: In vitro cytotoxicity tests have been conducted to evaluate the impact of the system on cell viability, ensuring safety at the cellular level. The Oral Mucosal Irritation tests and the GPMT have been carried out to provide insights into potential irritation, allergic reactions, and/or skin sensitization issues, which are critical aspects in evaluating the drug’s safety in practical applications.

The Effectiveness of the Technology  has been evaluated in terms of its ability to form a film and protect the mucous membranes. Prior to evaluation, an instrumental test was performed to assess the mucoadhesive properties of the technology. To determine the mucoprotective capacity, a cell viability assay, Mucoadhesion Test, Viability test, TEER measurement, and morphological analysis were performed on reconstructed esophageal mucosa exposed to a solution of hydrochloric acid (HCl 10%).

COMPLIFE. COMMITTED TO SCIENCE, COMMITTED TO YOU.