New Study by Complife: Atopic Dermatitis in Babies, Children and Adults

Published On: 7 September 2023

Atopic dermatitis (AD) is a chronic inflammatory and pruritic skin disease arising during the first months of life or at maturity.

In this clinical study, we studied the efficacy of a treatment based on daily use of three cosmetic products: a liquid emollient cleanser, an emollient cream for the body, and an emollient facial cream.

COMPLIFE enrolled 60 volunteers divided in 3 groups of twenty each (G1/G2/G3) that included subjects of 6-36 months, 3-14 years old and + 18 years old, with clinical signs of AD.

 

All the volunteers were enrolled by a pediatrician and a dermatologist and were assigned to active or placebo treatments.

 

The volunteers were distributed between our laboratories in the north and south of Italy: G1 and G3 studies were conducted in Complife Italia Srl in San Martino Siccomario, Pavia, Italy; while the study on G2 group was conducted in Nutratech (a Complife Italia Company) in Rende, Cosenza Italy.

TESTING METHODS

 

The product effect on AD clinical signs was investigated by:
– SCORing Atopic Dermatitis (SCORAD) index

The calculation of SCORAD is based on the extent of lesions, on the intensity of lesions (erythema, edema/papulation, oozing/crusts, excoriations, lichenification, dryness), and on subjective symptoms scoring (itching and sleep loss) This item was evaluated with the parents’ collaboration for groups 1 and 2.

– Skin erythema index

The erythema index was measured with Mexameter® MX 18 (Courage+Khazaka Electronic, Köln, Germany) which specifically measures hemoglobin content (erythema) in the skin. Measurements were performed on a skin area showing AD signs on the face and body.

-Transepidermal water loss (TEWL) measurements
The transepidermal water loss (TEWL, perspiratio insensibilis) was measured using a Tewameter® TM 300 (Courage+Khazaka Electronic, Köln, Germany). Tewameter® probe measures indirectly the density gradient of water evaporation over the skin surface using two pairs of sensors (temperature and relative humidity)

“READ THE RESULTS AND THE COMPLETE STUDY HERE”https%3A%2F%2Fwww.mdpi.com%2F2079-9284%2F10%2F4%2F117

VINCENZO NOBILE

R&D MANAGER AND COSMETIC MARKET MANAGER

 

VALENTINA ZANOLETTI

Sales Manager

 

MARTA PISATI

In Vivo Safety and Efficacy Supervisor

COMPLIFE. COMMITTED TO SCIENCE, COMMITTED TO YOU.

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