Absorption / Penetration / Deposition efficacy

Absorption / Penetration / Deposition efficacy is assessed using different techniques: Absorption of a substance/product may be assessed after topical application on a biological matrix, measuring the amount of substance penetrating, absorbed and deposed on the meambrane. Used models includes synthetic membranes or biological matrices such as human reconstructed tissues (epidermis/full thickness skin/epithelia), human skin…

Bacterial adhesion / Anti-adhesion efficacy

Bacterial adhesion / Anti-adhesion efficacy These biological assays – performed on different cell cultures or reconstructed tissues, depending on the intended product application – are aimed at assessing the product capacity to decrease the adhesion and proliferation of pathogenic bacteria and also to monitor the colonization by beneficial probiotic bacteria. Claims Adhesion / Anti-adhesion -…

Pigmenting and whitening

Pigmenting and whitening Biochemical assays focus on quantification of Dopachrome (precursor of melanin biosynthesis) and biological assays are performed on cell cultures (normal human primary epidermal melanocytes or mouse melanocytes B16) or reconstructed tissues (reconstructed human pigmented epidermis). The examined endpoints are melanin dosage, histology (H&E – FM staining) and microscopic/macroscopic observation. Claims Pigmenting and…

Astringent Effect

Astringent Effect: Astringent efficacy is measured by means of a 3D image analysis technique. Claims Astringent efficacy Reduces/minimizes pores size Other techniques Digital macrophotography Clinical evaluation of the pores astringent effect/efficacy Self-assessment (consumer test) ServicesAuditingCertificationConsultingInspectionTests and AnalysisChemical AnalysisEfficacy TestsMicrobiological TestsSafety TestsTraining Markets Cosmetics Medical Devices Get more info about this testDiscover how your dedicated expert…

Anti Sebum

Anti Sebum Anti sebum (oily skin and hair) effect is assessed through a spectrophotometric method able to measure the skin sebum content. Instrumental evaluations may be associated with clinical/dermatological assessment. Claims Reduces oily skin and hair appearance Regulates skin and scalp oil content Other techniques Digital macrophotography Clinical analysis of the sebum normalizing efficacy and/or…

Anti Couperose

Anti Couperose The facial conditions of affected subjects are screened by skilled dermatologists in order to evaluate the main signs of couperose: skin redness dryness spider veins stinging sensation Claims Improve the skin condition in subjects with couperose Other techniques Colorimetry Corneometry Self-assessment (consumer test) ServicesAuditingCertificationConsultingInspectionTests and AnalysisChemical AnalysisEfficacy TestsMicrobiological TestsSafety TestsTraining Markets Cosmetics Medical…

Anti ageing and Anti wrinkle test

Anti ageing/wrinkle efficacy is assessed using different techniques: Wrinkle surface/depth/volume is measured using a real 3D camera, while skin surface properties are measured using bioengineering techniques. Instrumental evaluations may be associated with clinical/dermatological assessment. Claims Anti ageing/wrinkle efficacy Anti wrinkle effect (after single product application) Improvement of skin smoothness Other techniques Skin moisturizing Skin elasticity…

Body Composition Analysis

Body composition analysis Bioelectrical impedance analysis (BIA) is a method commonly used to measure body composition (Fat Mass, Lean Mass, Intra- and Extracellular water, Basal metabolism rate, and muscle) Claims Decrease of fat mass Decrease of extracellular water Other techniques Adipometry (subcutaneous adipose tissue measurement) Plicometry (subcutaneous adipose tissue measurement) Self-assessment (consumer test) ServicesAuditingCertificationConsultingInspectionTests and…

Barrier Effect

Barrier Effect: Transepidermal water loss (TEWL, also known as perspiratio insensibilis) is a normal, constitutive loss of water vapour from the skin in the absence of sweat gland activity. However, as soon as the skin barrier function is slightly damaged, water loss increases. TEWL is therefore a measure of skin barrier function. Claims Skin barrier…