Patch and Controlled Tests

Patch and Controlled Tests: Human patch and controlled testing is a branch of our safety assessment program aimed at evaluating the effects of products coming into contact with the skin: Irritation (skin inflammation resulting in skin redness and swelling) Photo-irritation (skin inflammation resulting in skin redness and swelling after UV exposure) Sensitization (elicitation of an…

Antimicrobial efficacy of intimate hygiene products

Antimicrobial efficacy of intimate hygiene products is assessed using different techniques: Antimicrobial efficacy for intimate hygien products activity can be preliminarly evaluated through microbiological in-vitro testing vs. Candida albicans. Antimicrobial efficacy according to specifically designed testing methods Claims antimicrobial ServicesAuditingCertificationConsultingInspectionTests and AnalysisChemical AnalysisEfficacy TestsMicrobiological TestsSafety TestsTraining Markets Cosmetics Medical Devices Nutrition Get more info about…

Antimicrobial efficacy of detergents

Antimicrobial efficacy of detergents is assessed using different techniques: Antimicrobial efficacy for chemical disinfectants and antiseptcs – used in food, industrial, domestic and institutional applications – is assessed through microbiological in vitro testing according to international standards, with specific tests for handrub, handwash, surfaces applications. Quantitative suspension test for the evaluation of bacteria (EN 10…

Antiplaque

Antiplaque efficacy is assessed using different techniques: Antimicrobial efficacy for Antiplaque of oral care products can be preliminarly evaluated through microbiological in vitro testing according to international standards specifically modified for this purpose. Minimial Inhibitory Concentration (MIC) vs. S. mutans, S. mitis, L fermentum and F. nucleatum; Antiplaque efficacy according to EN standards vs. S.…

Anti acne

Anti acne efficacy is assessed using different techniques: Antimicrobial efficacy testing is an useful step to screen the efficacy of ingredients/products in counteracting the bacteria involved in the onset/development of acne. The inhibitory concentration of the ingredient/product on Propionibacterium acnes and Staphylococcus epidermidis growth is assessed through microbiological tests carried out according to the international…

Instrumental analyses

Instrumental analyses: Instrumental analyses are developed to evaluate physical and mechanical properties of a test substance. Main experimental test methods include: Water resistance/very water resistance/Waterproofness evaluation for make-up products and medical devices; volumizing and lengthening effect evaluation. PMMA plates for spectrophotometer readings or ex-vivo hair, in place of eyelashes, for macroscopic and microscopic image analysis…

Wound healing / Reparative efficacy

Wound healing / Reparative efficacy is assessed using different techniques: Morphological and histological analyses are conducted to evaluate the efficacy of a product in healing an artificial wound induced on cell monostrate or reconstructed tissues: Distance reduction of the wound edges are measured, while cell viability, protein metabolism and interleukin and cytokeratin panel are assessed…

Antinflammatory / Soothing efficacy

Antinflammatory / Soothing efficacy is assessed using different techniques: Inflammatory enzymes such as cyclooxygenase (COX) and lipoxygenase (LOX) are dosed through biochemical assays in order to assess the product efficacy to neutralize or sooth inflammatory stress conditions. Biological assays on cell cultures or reconstructed tissues are a valid alternative to monitor COX and LOX pathways,…

Protection from damage agents

Protection from damage agents efficacy is assessed using different techniques: Possible damage agents related to skin stress conditions are: Heavy metals / urban powder / synthetic smoke (environmental pollution); chemical irritating agents; biological inflammatory agents; photo-induced injuries (UV irradiation); oxidizing agents (oxidative stress). Biochemical kinetic and colorimetric assays are usually performed to quantify antioxidant enzyme…

Trophic / Energizing / Contraction efficacy

Trophic / Energizing / Contraction efficacy efficacy is assessed using different techniques: The extracellular matrix (ECM) dissociating enzymes (collagenase, elastase, hyaluronidase) are generally involved in cell metabolic pathways related to cell energy status, aging and skin trophic disorders. Biochemical assays can be useful to measure the marker enzyme activity, as well as the biological assays…