Sensitization

Sensitization efficacy is assessed using different techniques: Sensitization tests are useful to assess whether the product in exam may cause adverse effects involving immunological mechanisms; in vitro methods are currently under validation process. The human Cell Line Activation Test (h-CLAT) quantifies the induction of protein markers on the surface of THP-1 cell lines after exposure to…

Phototoxicity

Phototoxicity: Phototoxicity (photoirritation) is the toxic response of a cell model (Balb/c 3T3 cell line) to the test product when exposed to the light. The assay is carried out on products able to absorb the UV light or products that are applied under light exposure (i.e. day creams, sunscreens, etc.). The assay is performed according…

Home Use test under ophthalmologist control

Home Use test under ophthalmologist control Home-use test under ophthalmologist control is aimed to assess the tolerability of cosmetic products/suncreens/cosmetotextile products/household products, under real conditions of use. The product is delivered to the subjects for a daily regular use; at fixed experimental times the ophthalmologist evaluates the absence of adverse signs. Claims Tolerance tested Tested…

Home Use test under dermatologist control

Home Use test under dermatologist control Home-use test under dermatologist control is aimed to assess the tolerability of cosmetic products/suncreens/cosmetotextile products/household products, under real conditions of use. The product is delivered to the subjects for a daily regular use; at fixed experimental times the dermatologist evaluates the absence of adverse signs. Claims Tolerance tested Tested…

Home use test

Home use tests: Home use tests are aimed to evaluate the tolerability of products under real conditions of use. The product is supplied to the subjects for a daily regular use. Product tolerability is assessed by a highly skilled specialist at fixed experimental times. Claims Tolerance tested Tested under medical supervision For sensitive skin For…

Flex Wash Test

Flex Wash Test: The antecubital fossa of the arm (flex area) is the test skin area for the Flex Wash Test. Two products are generally compared and tested at the same time. This test is helpful to discriminate the mildness or the irritancy of personal cleansing products. All wash treatments are performed under the supervision of…

Photopatch Test

Photopatch Test The photopatch test is aimed to assess the incidence of skin irritation which may be induced by the test product when applied on the skin up to 48 hours and after UV exposure. The test is carried out on healthy subjects under occlusive/semi-occlusive/open conditions, depending on product category. Skin reactions (redness and swelling)…

Human Repeated Insult Patch (HRIPT), Shelansky & Shelansky / Marzulli & Maibach

Human Repeated Insult Patch (HRIPT), Shelansky & Shelansky / Marzulli & Maibach: The Human Repeated Insult Patch Test is aimed to assess the incidence of skin sensitization which may be induced by the test product when repeatedly applied on the skin. The test is carried out on healthy subjects under occlusive/semi-occlusive/open conditions, depending on the…