Complife is a worldwide group, which provides consulting and testing services for food, food supplements, household products, cosmetotextiles, cosmetics and pharma companies.

Antiplaque

Antiplaque efficacy is assessed using different techniques: Antimicrobial efficacy for Antiplaque of oral care products can be preliminarly evaluated through microbiological in vitro testing according to international standards specifically modified for this purpose. Minimial Inhibitory Concentration (MIC) vs. S. mutans, S. mitis, L fermentum and F. nucleatum; Antiplaque efficacy according to EN standards vs. S.…

Coadjuvant in the treatment of acne

Anti acne efficacy is assessed using different techniques: Antimicrobial efficacy testing is a useful step to screen the efficacy of ingredients/products in counteracting the bacteria involved in the onset/development of acne. The inhibitory concentration of the ingredient/product on Propionibacterium acnes and Staphylococcus epidermidis growth is assessed through microbiological tests carried out according to international recognized…

Sun protection (SPF, UVAPF, WR)

Sun Protection¬†efficacy is assessed using different techniques: Sun Protection efficacy. Our testing services include UVA protection, Sun Protection Factor (SPF), and Water Resistance (WR) assessment according to the relevant methods compliant with European, American, Canadian, Australian, and Asian requirements. Sun protection test includes both in vitro and in vivo (on humans) methods. Claims UVA Protection…

Wound healing / Reparative efficacy

Wound healing / Reparative efficacy is assessed using different techniques: Morphological and histological analyses are conducted to evaluate the efficacy of a product in healing an artificial wound induced on cell monostrate or reconstructed tissues: Distance reduction of the wound edges are measured, while cell viability, protein metabolism and interleukin and cytokeratin panel are assessed…

Antinflammatory / Soothing efficacy

Antinflammatory / Soothing efficacy is assessed using different techniques: Inflammatory enzymes such as cyclooxygenase (COX) and lipoxygenase (LOX) are dosed through biochemical assays in order to assess the product efficacy to neutralize or sooth inflammatory stress conditions. Biological assays on cell cultures or reconstructed tissues are a valid alternative to monitor COX and LOX pathways,…

Protection from damage agents

Protection from damage agents efficacy is assessed using different techniques: Possible damage agents related to skin stress conditions are: Heavy metals / urban powder / synthetic smoke (environmental pollution); chemical irritating agents; biological inflammatory agents; photo-induced injuries (UV irradiation); oxidizing agents (oxidative stress). Biochemical kinetic and colorimetric assays are usually performed to quantify antioxidant enzyme…

Trophic / Energizing / Contraction efficacy

Trophic / Energizing / Contraction efficacy efficacy is assessed using different techniques: The extracellular matrix (ECM) dissociating enzymes (collagenase, elastase, hyaluronidase) are generally involved in cell metabolic pathways related to cell energy status, aging and skin trophic disorders. Biochemical assays can be useful to measure the marker enzyme activity, as well as the biological assays…

Absorption / Penetration / Deposition efficacy

Absorption / Penetration / Deposition efficacy is assessed using different techniques: Absorption of a substance/product may be assessed after topical application on a biological matrix, measuring the amount of substance penetrating, absorbed and deposed on the meambrane. Used models includes synthetic membranes or biological matrices such as human reconstructed tissues (epidermis/full thickness skin/epithelia), human skin…

Bacterial adhesion / Anti-adhesion efficacy

Bacterial adhesion / Anti-adhesion efficacy These biological assays – performed on different cell cultures or reconstructed tissues, depending on the intended product application – are aimed at assessing the product capacity to decrease the adhesion and proliferation of pathogenic bacteria and also to monitor the colonization by beneficial probiotic bacteria. Claims Adhesion / Anti-adhesion -…